Has anybody tried to install Aspen Suites in Linux ?

I am considering moving my OS from Windows to Linux.

At the worst condition I can install using VirtualBox.

I think .net framework works under WINE (Windows emulator) in Linux.
I do not have any idea about SQL Express 2008 R2 in Wine.

Also, fyi, Almost most famous softwares like Photoshop, MS Word, Games runs flawlessly in Linux under Wine.